Luma Nano Dark Spot Remover incorporate nano particles that are being produced in USA, has been tested for endotoxin, and is certified safe for numerous applications for medical diagnostics, therapeutics, and cosmetic uses. Luma Nano Dark Spot Remover utilizes the nano particles as a delivery agent to help pass the ingredients deeper through skin and tissue, efficacious for treating dark spots. Noticeable improvement for dark spot can be seen in as little as 2 weeks.